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The IRA Just Rewrote the 340B Playbook. Most Programs Haven’t Caught Up.

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Q1 2026 started rougher than predicted for 340B programs. Ceiling prices compressed. Penny pricing disappeared on drugs that used to be your biggest savings. And an entire drug category that looked like a growth engine 12 months ago went dark almost

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NuvemRx

Q: Tell us some interesting details about your company’s history.

NuvemRx began with the merging of three organizations: 340Basics, Apovia, and Louvir. In 2024, these teams came together to

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340B INDUSTRY LEADER SPOTLIGHT

Colleen DiClaudio, President and Founder, Nuvem

Colleen DiClaudio

Q: Where did you grow up?

I grew up in a rural area of Southern New Jersey, which is just about halfway between Philadelphia, PA and the Jersey Shore, as well as just over an hour away from New York City. This location made it easily accessible to experience the liveliness of the city while also enjoying

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