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In 1999, the Centers for Disease Control and Prevention (CDC) launched the National Campaign to Eliminate Syphilis from the United States. The CDC updated its ambitious plan in 2006 and aimed to reduce rates of primary and secondary syphilis to less than 2.2 cases per 100,000 population, congenital syphilis to less than 3.9 cases per 100,000, and the racial disparity between rates of syphilis among Black and White individuals to less than 3:1. Despite having moderate success at the turn of the century, the US is experiencing a drastic resurgence of syphilis. In 2021, the CDC reported 171,074 total cases of syphilis nationally, a 68.4% increase from 2017. Worse, there has been a sharp increase in the number of babies born with syphilis; cases of congenital syphilis rose 184.5% to 2,677 cases between 2017 and 2021.
Like other sexually transmitted infections (STIs), syphilis disparities remain with regards to
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