
Q: Tell us some interesting details about your company’s history.
RxParadigm, founded by industry veteran Mesfin Tegenu, is dedicated to developing technology solutions that streamline the drug supply chain and eliminate inefficiencies. In response to the growing challenges that 340B stakeholders face —along with ongoing debates over eligibility, legal challenges, legislative changes, and increasing restrictions—RxParadigm has built the nation’s first neutral 340B clearinghouse with the goal of bringing stability and transparency to the program. In order for a clearinghouse to get buy in from all parties — 340B covered entities, the drug industry and government—it is critically important for it not be beholden to any particular industry stakeholder.
With nearly 30 years of expertise, RxParadigm continues to deliver innovative technology solutions that drive meaningful outcomes for clients. The company’s commitment to efficiency and compliance also extends to its work on an upcoming Medicare Maximum Fair Price (MFP) solution to help resolve challenges in IRA implementation. Guided by a leadership team with deep expertise in pharmacy and technology, RxParadigm has developed its flagship Tungsten+PLUS™ Clearinghouse Solution to help stakeholders navigate today’s complex healthcare landscape.

Q: Provide some fun facts about your company:
- Coast-to-Coast Crew – Our team is sprinkled across the U.S., making RxParadigm a true nationwide powerhouse!
- 340B Superhero – Tungsten+PLUS™ swoops in to stop duplicate payments and keep data locked up tighter than Fort Knox.
- VIP List Approved – Major hospitals, state PCAs, and drug manufacturers are jumping on board—because who doesn’t love a game-changer?
- Built for the Future – Our clearinghouse doesn’t just keep up with regulations—it stays ahead of them (looking at you, IRA MFP!).
- Where Tech Meets Pharmacy – Like peanut butter and jelly, we mix innovation with pharmacy smarts to make the drug supply chain smoother.
- Making Compliance Cool – Okay, maybe not cool, but definitely easier, faster, and way less of a headache!
Q: What makes your company unique in the 340B space?
RxParadigm is dedicated to improving efficiency in the 340B program through a neutral and transparent clearinghouse. Tungsten+PLUS™ helps manufacturers, payers, and healthcare providers by eliminating duplicate discounts and improving claims identification.
By moving away from unreliable claim modifiers, Tungsten+PLUS™ ensures claims are validated and certified with accuracy, helping to restore confidence in the 340B process. Our commitment to data privacy and security is backed by HITRUST certification, and our solution has been widely adopted by hospital systems, state PCAs, and drug manufacturers.
At RxParadigm, we remain focused on building technology that brings clarity, compliance, and trust to the 340B program through collaborative partnerships with stakeholders.
Q: What about your company’s work are you most proud of?
At RxParadigm, we take pride in our ability to build bridges between stakeholders who, for years, have viewed each other with suspicion. We’re honored to partner with our clients in rolling out Tungsten+PLUS™, a neutral 340B clearinghouse designed to bring much-needed transparency and put an end to duplicate discounts.
We’re especially proud to collaborate with health centers, primary care organization associations, DSH hospitals, hospital associations, drug manufacturers, and many others to make this vision a reality. As a truly neutral third party, our mission is simple: bring Covered Entities, TPAs, Manufacturers, Health Plans, and Pharmacies to the same table—without food fights—so we can restore stability, improve transparency, and eliminate double payments while ensuring the 340B program continues to serve those who need it most.
Click here to learn more about RxParadigm or for questions email: carlo.cioffi@rxparadigm.com.
