Expert Tip from SpendMend

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TIP: Optimize NDC selection by evaluating utilization, not just 340B accumulations.


When selecting a preferred National Drug Code (NDC) within a medication grouping (e.g., lisinopril 10 mg), many covered entities (CEs) focus solely on available 340B accumulations. While important, this can lead to suboptimal choices if historical utilization across all account types (340B, GPO, WAC) is not also considered.

Instead, analyze utilization patterns to calculate a weighted price for each NDC based on how often it’s used under each pricing category. This ensures you’re selecting the NDC that offers the best net value—not just the most 340B savings in isolation.

Additional considerations:

  1. It may still make sense to purchase the remaining 340B accumulations before transitioning to a new NDC.
  2. Factor in operational impacts—e.g., unit dose vs. bulk bottle, vial vs. syringe, or alignment with committed contracts.
  3. With most CEs managing over 4,000 medication groupings, manual optimization is not scalable.

That’s where a tool like Trulla Procurement adds value. Trulla automates NDC optimization by factoring in historical utilization, contract pricing, and operational preferences—giving pharmacy buyers data-driven recommendations at scale.

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